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1

Epigenome-wide association studies for common human diseases

Rakyan, Vardhman K., Down, Thomas A., Balding, David J., Beck, Stephan

Journal:

Nature Reviews Genetics

Year:

2011

Language:

english

File:

PDF, 440 KB

english, 2011

2

A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis

Down, Thomas A, Rakyan, Vardhman K, Turner, Daniel J, Flicek, Paul, Li, Heng, Kulesha, Eugene, Gräf, Stefan, Johnson, Nathan, Herrero, Javier, Tomazou, Eleni M

Journal:

Nature Biotechnology

Year:

2008

Language:

english

File:

PDF, 984 KB

english, 2008

3

Metastable epialleles in mammals

Vardhman K Rakyan, Marnie E Blewitt, Riki Druker, Jost I Preis, Emma Whitelaw

Journal:

Trends in Genetics

Year:

2002

Language:

english

File:

PDF, 47 KB

english, 2002

4

Transgenerational inheritance of non-genetically determined phenotypes

Holland, Michelle L., Rakyan, Vardhman K.

Journal:

Biochemical Society Transactions

Year:

2013

Language:

english

File:

PDF, 423 KB

english, 2013

5

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus

Bell, Christopher G., Finer, Sarah, Lindgren, Cecilia M., Wilson, Gareth A., Rakyan, Vardhman K., Teschendorff, Andrew E., Akan, Pelin, Stupka, Elia, Down, Thomas A., Prokopenko, Inga, Morison, Ian M.

Journal:

Year:

2010

Language:

english

File:

PDF, 361 KB

english, 2010

6

The hunt for the epiallele

Sarah Finer, Michelle L. Holland, Lisa Nanty, Vardhman K. Rakyan

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 397 KB

english, 2011

7

Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis

Eleni M Tomazou, Vardhman K Rakyan, Gregory Lefebvre, Robert Andrews, Peter Ellis, David K Jackson, Cordelia Langford, Matthew D Francis, Liselotte Bäckdahl, Marcos Miretti, Penny Coggill, Diego Ottav

Journal:

BMC Medical Genomics

Year:

2008

Language:

english

File:

PDF, 4.68 MB

english, 2008

8

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

Christopher G Bell, Andrew E Teschendorff, Vardhman K Rakyan, Alexander P Maxwell, Stephan Beck, David A Savage

Journal:

BMC Medical Genomics

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

9

Extracellular ATP couples to cAMP generation and granulocytic differentiation in human NB4 promyelocytic leukaemia cells

Van Der Weyden, Louise, Rakyan, Vardhman, Luttrell, Brian M, Morris, Michael B, Conigrave, Arthur D

Journal:

Immunology & Cell Biology

Year:

2000

Language:

english

File:

PDF, 344 KB

english, 2000

10

DNA methylation profiling of human chromosomes 6, 20 and 22

Eckhardt, Florian, Lewin, Joern, Cortese, Rene, Rakyan, Vardhman K, Attwood, John, Burger, Matthias, Burton, John, Cox, Tony V, Davies, Rob, Down, Thomas A

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 362 KB

english, 2006

11

The methylome: approaches for global DNA methylation profiling

Stephan Beck, Vardhman K. Rakyan

Journal:

Trends in Genetics

Year:

2008

Language:

english

File:

PDF, 303 KB

english, 2008

12

Transgenerational epigenetic inheritance

Vardhman Rakyan, Emma Whitelaw

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 59 KB

english, 2003

13

Protection against De Novo Methylation Is Instrumental in Maintaining Parent-of-Origin Methylation Inherited from the Gametes

Proudhon, Charlotte, Duffié, Rachel, Ajjan, Sophie, Cowley, Michael, Iranzo, Julian, Carbajosa, Guillermo, Saadeh, Heba, Holland, Michelle L., Oakey, Rebecca J., Rakyan, Vardhman K., Schulz, Reiner, B

Journal:

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

14

Epigenetic variation and inheritance in mammals

Vardhman K Rakyan, Stephan Beck

Journal:

Current Opinion in Genetics & Development

Year:

2006

Language:

english

File:

PDF, 170 KB

english, 2006

15

Sites of Differential DNA Methylation between Placenta and Peripheral Blood: Molecular Markers for Noninvasive Prenatal Diagnosis of Aneuploidies

Elisavet A. Papageorgiou, Heike Fiegler, Vardhman Rakyan, Stephan Beck, Maj Hulten, Klea Lamnissou, Nigel P. Carter, Philippos C. Patsalis

Journal:

The American Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 224 KB

english, 2009

16

The hunt for mammalian epialleles

Vardhman Rakyan

Journal:

BMC Proceedings

Year:

2012

Language:

english

File:

PDF, 67 KB

english, 2012

17

Marmal-aid – a database for Infinium HumanMethylation450

Lowe, Robert, Rakyan, Vardhman K

Journal:

BMC Bioinformatics

Year:

2013

Language:

english

File:

PDF, 453 KB

english, 2013

18

Dipyrone misuse

Gemma, Carolina, Ramagopalan, Sreeram V, Down, Thomas A, Beyan, Huriya, Hawa, Mohammed I, Holland, Michelle L, Hurd, Paul J, Giovannoni, Gavin, David Leslie, R, Ebers, George C, Rakyan, Vardhman K

Journal:

Reactions Weekly

Year:

2013

Language:

english

File:

PDF, 128 KB

english, 2013

19

Amoxicillin/clavulanic acid

Gemma, Carolina, Ramagopalan, Sreeram V, Down, Thomas A, Beyan, Huriya, Hawa, Mohammed I, Holland, Michelle L, Hurd, Paul J, Giovannoni, Gavin, David Leslie, R, Ebers, George C, Rakyan, Vardhman K

Journal:

Reactions Weekly

Year:

2013

Language:

english

File:

PDF, 127 KB

english, 2013

20

Batch traceability of unsafe biodrugs needs to improve

Gemma, Carolina, Ramagopalan, Sreeram V, Down, Thomas A, Beyan, Huriya, Hawa, Mohammed I, Holland, Michelle L, Hurd, Paul J, Giovannoni, Gavin, David Leslie, R, Ebers, George C, Rakyan, Vardhman K

Journal:

Reactions Weekly

Year:

2013

Language:

english

File:

PDF, 111 KB

english, 2013

21

Daptomycin/linezolid/tigecycline

Gemma, Carolina, Ramagopalan, Sreeram V, Down, Thomas A, Beyan, Huriya, Hawa, Mohammed I, Holland, Michelle L, Hurd, Paul J, Giovannoni, Gavin, David Leslie, R, Ebers, George C, Rakyan, Vardhman K

Journal:

Reactions Weekly

Year:

2013

Language:

english

File:

PDF, 128 KB

english, 2013

22

Inactive or moderately active human promoters are enriched for inter-individual epialleles

Gemma, Carolina, Ramagopalan, Sreeram V, Down, Thomas A, Beyan, Huriya, Hawa, Mohammed I, Holland, Michelle L, Hurd, Paul J, Giovannoni, Gavin, David Leslie, R, Ebers, George C, Rakyan, Vardhman K

Journal:

Year:

2013

Language:

english

File:

PDF, 743 KB

english, 2013

23

1032 Host-Environment Interactions Shape the Risk for Ulcerative Colitis: Results From a Twin Epigenome-Wide Association Study

Haesler, Robert, Feng, Zhe, Bäckdahl, Liselotte, Spehlmann, Martina E., Franke, Andre, Teschendorff, Andrew, Rakyan, Vardhman, Down, Thomas A., Wilson, Gareth A., Feber, Andrew, Beck, Stephan, Schreib

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 342 KB

english, 2013

24

Correcting for cell-type composition bias in epigenome-wide association studies

Robert Lowe,Vardhman K Rakyan

Journal:

Genome Medicine

Year:

2014

Language:

english

File:

PDF, 100 KB

english, 2014

25

Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates

Hillman, Sara L, Finer, Sarah, Smart, Melissa C, Mathews, Chris, Lowe, Robert, Rakyan, Vardhman K, Hitman, Graham A, Williams, David J

Journal:

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

26

The human blood DNA methylome displays a highly distinctive profile compared with other somatic tissues

Lowe, Robert, Slodkowicz, Greg, Goldman, Nick, Rakyan, Vardhman K

Journal:

Year:

2015

Language:

english

File:

PDF, 2.35 MB

english, 2015

27

The promise and challenges of blood spot methylomics

Ramagopalan, Sreeram V, Rakyan, Vardhman K

Journal:

Year:

2013

Language:

english

File:

PDF, 542 KB

english, 2013

28

Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies

Lowe, Robert, Gemma, Carolina, Beyan, Huriya, Hawa, Mohammed I., Bazeos, Alexandra, Leslie, R. David, Montpetit, Alexandre, Rakyan, Vardhman K., Ramagopalan, Sreeram V.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.08 MB

english, 2013

29

Identification of Type 1 Diabetes–Associated DNA Methylation Variable Positions That Precede Disease Diagnosis

Rakyan, Vardhman K., Beyan, Huriya, Down, Thomas A., Hawa, Mohammed I., Maslau, Siarhei, Aden, Deeqo, Daunay, Antoine, Busato, Florence, Mein, Charles A., Manfras, Burkhard, Dias, Kerith-Rae M., Bell,

Journal:

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

30

Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development

Lowe, Robert, Gemma, Carolina, Rakyan, Vardhman K, Holland, Michelle L

Journal:

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

31

Extracellular ATP couples to cAMP generation and granulocytic differentiation in human NB4 promyelocytic leukaemia cells

WEYDEN, LOUISE VAN DER, RAKYAN, VARDHMAN, LUTTRELL, BRIAN M, MORRIS, MICHAEL B, CONIGRAVE, ARTHUR D

Journal:

Immunology & Cell Biology

Year:

2000

Language:

english

File:

PDF, 336 KB

english, 2000

32

Integrated analysis of genome-wide genetic and epigenetic association data for identification of disease mechanisms

Ke, Xiayi, Cortina-Borja, Mario, Silva, Bruno Cesar, Lowe, Robert, Rakyan, Vardhman, Balding, David

Journal:

Year:

2013

Language:

english

File:

PDF, 1.74 MB

english, 2013

33

The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Lowe, Robert, Overhoff, Marita G., Ramagopalan, Sreeram V., Garbe, James C., Koh, James, Stampfer, Martha R., Beach, David H., Rakyan, Vardhman K., Bishop, Cleo L.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.56 MB

english, 2015

34

The marks, mechanisms and memory of epigenetic states in mammals

RAKYAN, Vardhman K., PREIS, Jost, MORGAN, Hugh D., WHITELAW, Emma

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 207 KB

english, 2001

35

The marks, mechanisms and memory of epigenetic states in mammals

RAKYAN, Vardhman K., PREIS, Jost, MORGAN, Hugh D., WHITELAW, Emma

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 207 KB

english, 2001

36

Correlation of an epigenetic mitotic clock with cancer risk

Yang, Zhen, Wong, Andrew, Kuh, Diana, Paul, Dirk S., Rakyan, Vardhman K., Leslie, R. David, Zheng, Shijie C., Widschwendter, Martin, Beck, Stephan, Teschendorff, Andrew E.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.06 MB

english, 2016

37

eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data

Breeze, Charles E., Paul, Dirk S., van Dongen, Jenny, Butcher, Lee M., Ambrose, John C., Barrett, James E., Lowe, Robert, Rakyan, Vardhman K., Iotchkova, Valentina, Frontini, Mattia, Downes, Kate, Ouw

Journal:

Year:

2016

Language:

english

File:

PDF, 4.75 MB

english, 2016

38

DNA methylation profiles between airway epithelium and proxy tissues in children

Brugha, Rossa, Lowe, Robert, John Henderson, A., Holloway, John W., Rakyan, Vardhman, Wozniak, Eva, Mahmud, Nadiya, Seymour, Kay, Grigg, Jonathan, Shaheen, Seif O.

Journal:

Acta Paediatrica

Year:

2017

Language:

english

File:

PDF, 285 KB

english, 2017

39

Early life diet conditions the molecular response to post-weaning protein restriction in the mouse

Danson, Amy F., Marzi, Sarah J., Lowe, Robert, Holland, Michelle L., Rakyan, Vardhman K.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

40

BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files

Payne, Alexander, Holmes, Nadine, Rakyan, Vardhman, Loose, Matthew, Birol, Inanc

Journal:

Year:

2018

Language:

english

File:

PDF, 1.42 MB

english, 2018

41

The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations

Ãsenius, Fredrika, Gorrie-Stone, Tyler J., Brew, Ama, Panchbhaya, Yasmin, Williamson, Elizabeth, Schalkwyk, Leonard C., Rakyan, Vardhman K., Holland, Michelle L., Marzi, Sarah J., Williams, David J.,

Journal:

Year:

2020

File:

PDF, 3.47 MB

2020

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